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Combantrin-1 products are different from the other Combantrin products in that they use mebendazole as the active ingredient instead of pyrantel embonate. They offer a one tablet, once only, treatment for pinworms / threadworms. Combantrin-1 with mebendazole can be used by children over 2 years of age.

Mebendazole is an anthelmintic, meaning an agent designed to destroy parasitic intestinal worms, that works by interfering with the proteins in either the worm's intestine or absorptive cells. This inhibits the threadworms’ ability to absorb glucose (sugars) which depletes them of the energy that they need to survive. As a result the threadworm dies within several days.


Combantrin-1 chocolate squares each contain 100mg of mebendazole. Combantrin-1 chocolate squares are available in packs of 4 chocolate squares, enough to treat 4 people for threadworm.

Side effects: Side effects with Combantrin-1 chocolate squares with mebendazole are unusual but can include diarrhoea or abdominal pain. These are often only short term side effects and may be related to the size of the threadworm infestation but see your doctor if symptoms persist.

Other infections: Roundworm, whipworm and hookworm infections can be treated with Combantrin-1 chocolate squares but you should seek medical advice before beginning treatment if you suspect that you have any of these worm infections because they are difficult to diagnose.

Caution: You should not use Combantrin-1 chocolate squares if you are pregnant. Do not give Combantrin-1 chocolate squares to children under two years of age. If you are unsure about either of these restrictions then consult your doctor. You should not take Combantrin-1 if you are allergic to, or have a hypersensitivity to, any of its ingredients. Caution is also required if you suffer from acute liver disease or are taking the anti-ulcer medication Cimetidine. In either of these cases, long-term treatment with mebendazole can lead to an excessive plasma concentration in the blood when the liver does not breakdown the mebendazole sufficiently. Caution should also be taken if you using the anticonvulsant Carbamazepine.

Dosage: Take only one Combantrin-1 chocolate square, regardless of your body weight, with or without food, to kill threadworm in adults and children over 2 years of age.

Combantrin-1 chocolate squares contain no gluten, artificial colours or artificial flavours, to the equivalent to less than 0.3% W/W. The chocolate squares do contain lactose, sucrose. The appearance of the chocolate squares may alter slightly with storage but this does not affect the quality or effectiveness of the product.

Other Combantrin products include: Combantrin Chocolate Squares, Combantrin Suspension, and Combantrin Tablets.

You can order this product by following the link below.

We are no longer accepting orders through WormTreatment.com, but you can still purchase from us at our main website below. You'll receive the same excellent service, from the same people.

Click here to purchase Combantrin-1.

Combantrin is a registered trademark of Pfizer Inc. Pfizer Pty Ltd 38-42 Wharf Road, West Ryde, NSW 2114 Australia. Pfizer Laboratories Limited, Auckland, New Zealand